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Tirzepatide, a dual glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 receptor agonist (GLP-1 RA), has shown superior efficacy in glycemic control, weight loss and cardiometabolic outcomes compared to GLP-1 agonists alone
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Prediction markets and analyst estimates As of early 2026, prediction markets place the probability of FDA approval this year at approximately 27%
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