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Routine monitoring of serum calcitonin or using thyroid ultrasound is of uncertain value for early detection of MTC in patients treated with (MOUNJARO OR ZEPBOUND) [see Contraindications (4) and Warnings and Precautions (5.1)].” Trulicity has the following boxed warning (2025) (formerly known as a black box warning), related to dulaglutide the main ingredient in Trulicity, set forth below: “WARNING: RISK OF THYROID C-CELL TUMORS • In male and female rats, dulaglutide causes a dose-related and treatment-duration-dependent increase in the incidence of thyroid C-cell tumors (adenomas and carcinomas) after lifetime exposure
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