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For a while, one of the big worries in obesity pharmacotherapy has been pretty simple: when body weight drops fast, how much of that is fat, and how much is the tissue
Unlike peripheral GLP-1, which acts mainly through endocrine and paracrine pathways, c-GLP-1 exerts neurocrine effects, influencing hypothalamic and limbic circuits
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Yet, there is neither data on the transport and possible consequences of bacterial-derived proteins in EEC nor on the expression of NLR in EEC
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