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For the treatment of non-metastatic castration-resistant and metastatic castration-sensitive prostate cancer, clinical guidelines recommend androgen receptor antagonists, such as apalutamide, in combination with androgen-deprivation therapy as the standard of care

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DISCUSSION With the prevalence of diabetes and obesity rising, therapeutic strategies that facilitate weight loss, improve glycemic control, and reduce cardiovascular risk should be emphasized.13 Agents in the GLP-1 RA class meet most or all of these criteria