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new oral glp 1 agonist In the ACHIEVE-1 phase 3 trial, the small-molecule GLP

As GLP-1 drugs demonstrate outcomes beyond weight loss, payers and health systems are increasingly evaluating them as tools for reducing downstream medical costs

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Thus, SGLT2 inhibition results in increased excretion of both glucose and sodium, leading to a reduction in intravascular volume and arterial smooth muscle sodium content, both of which would be expected to reduce the blood pressure