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Furthermore, therapeutic interventions for the treatment of obesity and liver metabolic diseases are also discussed with a focus on restoring the gut-liver axis
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The NF-κB and Nrf2 pathways are two important pathways that mediate cellular homeostasis by controlling neuroinflammation, while the MAPK pathway is a classical pathway that can indirectly or directly initiate the production of inflammatory mediators and activation of NF-κB (146)
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