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By medical definition, an agonist “is a manufactured substance that attaches to a cell receptor and causes the same action as the naturally occurring substance.” Named after the GLP-1 hormone or glucagon-like-peptide-1, the agonist medications work by mimicking the blood-lowering capacity of this hormone

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14 Cardiovascular Outcomes Meta-Analyses: Numerous meta-analyses, including one published in , have systematically reviewed multiple GLP-1 trials and confirmed that the class of drugs as a whole significantly reduces MACE, all-cause mortality, and cardiovascular mortality