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In the 1980s, researchers at the NIH were studying something that seemed purely curiosity-driven: venom from the Gila monster, a desert lizard., What they found changed medicine., A molecule in that ...

Disclosures: Isaac Israel Rodriguez Salazar: Nothing to Disclose, Andreas Teufel: Nothing to Disclose, Abhinay Vellala: Nothing to Disclose, Timo Itzel: Nothing to Disclose, Jimmy Daza: Nothing to Disclose, Michael Vácha: Nothing to Disclose, Manuel Debic: Nothing to Disclose, De-Hua Chang: Nothing to Disclose, Michael Dill: Nothing to Disclose, Max Seidensticker: Nothing to Disclose, Gerd Oswald Stefan Schönberg: Nothing to Disclose, Lukas Müller: Nothing to Disclose, Julia Mayerle: Nothing to Disclose, Stefan Munker: Nothing to Disclose, Peter Galle: Bayer: Consultant, Roche: Advisor, Eisai: Advisor, AstraZeneca: Advisor, BMS: Advisor, MSD: Advisor, Guerbet: Advisor, Arndt Weinmann: Servier: Advisor, Abbview: Speaking and Teaching, AstraZeneca: Speaking and Teaching, Incyte: Advisor, Taiho: Advisor, Roche: Speaking and Teaching, Dietmar Tamandl: Nothing to Disclose, Matthias Pinter: BMS: Consultant, AstraZeneca: Consultant, Eisai: Consultant, Ipsen: Speaking and Teaching, Roche: Consultant, MSD: Speaking and Teaching, Marino Venerito: Nothing to Disclose, Matthias Ebert: Nothing to Disclose, Matthias Froelich: Nothing to Disclose, Maciej Pech: Nothing to Disclose, Friedrich Sinner: Nothing to Disclose, Bernhard Scheiner: Nothing to Disclose 1876 SPATIAL OMICS ANALYSIS OF THE PROXIMITY OF PD-L1(+) TUMOR-ASSOCIATED MACROPHAGE AND CD8T CELL INTERACTION PROMOTING HEPATOCELLULAR CARCINOMA PROGRESSION Takuto Nosaka 1 Masahiro Ohtani 1 Junki Yamashita 1 Yosuke Murata 1 Tomoko Tanaka 1 Yu Akazawa 1 Kazuto Takahashi 1 Tatsushi Naito 1 Yasunari Nakamoto 1 , 1 University of Fukui Background: Spatial omics technology enables visualization of the tumor immune microenvironment and analysis of immune cell interactions

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Mounjaro's dual indication creates a coverage split under Medicare: Covered: Mounjaro for type 2 diabetes (FDA-approved indication) Excluded: Zepbound for chronic weight management (same molecule, different brand name, different indication) If you have an Aetna Medicare Advantage plan and type 2 diabetes, Mounjaro is covered subject to prior authorization and step therapy