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Comparative effectiveness of GLP-1 receptor agonists on glycaemic control, body weight, and lipid profile for type 2 diabetes: systematic review and network meta-analysis | The BMJ

These heterogeneous responses are modulated by multiple factors, including tumor classification, study methodology, treatment duration, and patient-specific parameters (Table 1)

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7 Recognition of the role GLP-1 RAs play in systemic health has been reflected in clinical guidelines, with GLP-1 RAs recommended as first-line in the pharmacologic management of type 2 diabetes by the American Diabetes Association for patients with various systemic co-morbidities