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The Impact of GLP-1 Receptor Agonists on Sedation | DOCS Education
In addition, evidence suggests that GLP-1 RAs may increase pancreatic enzyme secretion, while the expression and subsequent stimulation of GLP-1 receptors in pancreatic islet and exocrine duct cells have been correlated with overgrowth of the ductal epithelial cells, resulting in hyperplasia and chronic low-grade or acute inflammation, potentially leading to pancreatitis [89]
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The clinical evidence behind GLP-1 active compounds as a class is substantial, drawn from large, controlled trials of FDA-approved formulations
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