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However, the best results are typically achieved when the injections are combined with a healthy, reduced-calorie diet and regular physical activity
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Patients on oral contraceptives should be advised to switch to a non-oral contraceptive method or add a barrier method for 4 weeks after initiation and for 4 weeks after each dose escalation." What this means in practice: The formal drug interaction study (Hausner et al., Clinical Pharmacokinetics , 2020) showed no change in oral contraceptive hormone levels (AUC, Cmax) in women taking semaglutide 1 mg weekly
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