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Glucagon receptors regulate hepatic glucose production and thermogenic fat burning — activating them alongside GLP-1 and GIP appears to substantially amplify the overall metabolic effect
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In this review article, we aimed to (1) confirm the association between HFpEF and obesity, (2) introduce the mechanisms and recent studies on GLP-1 RAs in HFpEF, and (3) suggest future therapeutic directions for obesity-associated HFpEF
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