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FDA has issued a box warning of the risk of thyroid cancers and are contraindicated liraglutide, exenatide (once weekly), and semaglutide (both oral and injectable) in patients with a personal or family history of medullary thyroid cancer or multiple endocrine neoplasia types 2 A or 2B [135, 136]
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[6] Whilst the precise neuropsychiatric effects of GLP-1 receptor agonists remain under investigation, it is theoretically possible that modulation of these pathways could influence emotional states in susceptible individuals
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