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Big development in weight management that matters for spine health. A new once-daily oral GLP-1 medication (orforglipron, now FDA-approved as Foundayo) outperformed the leading oral semaglutide in a major head-to-head phase 3
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In fact, a genetic Mendelian randomization study in 2024 found that having a genetic profile akin to being on GLP-1 RA therapy was associated with ~50% lower odds of ED, partly mediated by lower obesity, diabetes, and blood pressure
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