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These are analogs of GLP-1 with longer half-lives and sustained action, effectively enhancing insulin secretion and inhibiting glucagon release
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Dose:1 mg
Notably, activation of GLP-1R requires specific coordinated interactions with potential ligands, as observed in GLP-1 and Semaglutide
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![PDF] Discovery of the Once-Weekly Glucagon-Like Peptide-1 (GLP-1) Analogue Semaglutide](https://figures.semanticscholar.org/594349790d0e9a09f8b5843f2782af9cfaaa7bf4/37-Figure3-1.png)
