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Both are GLP-1 medications that are FDA-approved for Type 2 diabetes and weight loss, but how they work differs. Read more about them: https://health.clevelandclinic.org/tirzepatide-vs-semaglutide
However, given the connection to the GWAS data, at a minimum Zn 2+ is important for glucose control and a logical link for that is through inhibiting the release of glucagon
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The industry is highly concentrated: in 2024 Novo Nordisk had ~59% of revenue ($31.75B) and Eli Lilly ~41% ($21.72B) ( [25] ), reflecting dominance of weekly semaglutide and dulaglutide, with Lilly’s tirzepatide rapidly rising
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