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Gastrointestinal symptoms during dose changes Nausea, constipation, and other GI symptoms are the most common side effects of GLP-1 therapy, and they tend to re-emerge whenever dosing changes occur
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showed that the activation of GLP-1R by liraglutide led to an anti-tumor effect on human pancreatic cancer via the inhibition of the PI3K/AKT pathway (224)