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A 2025 substudy in adults with type 2 diabetes found that retatrutide significantly reduced fat mass and that its lean-mass loss proportion was similar to what has been seen in other obesity treatments

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“Emerging Evidence for the Importance of Dietary Protein Source on Glucoregulatory Markers and Type 2 Diabetes: Different Effects of Dairy, Meat, Fish, Egg, and Plant Protein Foods”