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GLP-1 receptor agonists are increasingly used to treat type 2 diabetes and obesity, and trials have shown reductions in cardiovascular risk and slowing of kidney failure. Adverse events are mostly gastrointestinal.
Tirzepatide (Mounjaro and Zepbound) at the 15 mg dose showed comparable lean-mass loss in pattern but modestly less in proportion (approximately 25% of total weight loss as lean mass
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That attachment helps it bind to albumin in the blood
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