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In the STEP 1 trial published in the New England Journal of Medicine (2021), participants receiving semaglutide 2.4 mg weekly achieved an average weight loss of approximately 15% of body weight over 68 weeks, compared to 2.4% with placebo

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Unreconstituted Retatrutide should be stored refrigerated and protected from light, and is commonly reconstituted with bacteriostatic water prior to research preparation