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dpp-4 inhibitors vs. glp-1 agonist receptor versus inhibitor and kidney and cardiovascular outcomes in clinical practice in type-2 diabetes The Role of SGLT 2 โ
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Phase 2 trial data (Jastreboff et al., NEJM 2023) demonstrated average weight reductions of approximately 17โ24% over 48 weeks โ notably higher than currently approved GLP-1 receptor agonists such as semaglutide, though direct comparisons are limited by differences in trial populations and designs
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