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Tale of two drugs Two of these GLP-1 receptor agonists are FDA-approved in formulations specifically designed for weight loss in people without diabetes: liraglutide (Saxenda) and semaglutide (Wegovy)
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While there is potential mechanistic overlap with DPP-4 inhibitors or dual GLP/GIP receptor agonists we focus the current review on GLP-1RAs due to preponderance and availability of longer-term data, as well as the significantly higher market penetrance of this drug class
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